A previous study using electroacupuncture on the ST36 (Zusanli) and BL60 (Kunlun) acupoints of AIA rats demonstrated the molecular mechanism of acupuncture of RA was found by reducing the expression of toll-like receptor 4, myeloid differentiation factor 88 (MYD88), and NF-κB which play an important role in treating adjuvant arthritis[20]. The gene discussed is TLR4; the disease is rheumatoid arthritis.