Fifteen percent of individuals with Alport syndrome are autosomal recessive inherited caused by homozygous or compound heterozygous mutations from both alleles of either COL4A3 or COL4A4 genes (Storey, Savige, Sivakumar, Abbs, & Flinter, 2013; Wang et al., 2014; Zhang et al., 2012). This evidence concerns the gene COL4A4 and Alport syndrome.