In addition, miRNAs are posttranscriptionally downregulate gene expression through translational repression and mRNA destabilization.41 A variety of miRNAs have been found to regulate tumorigenesis and responses to cancer treatment by inducing chemosensitization by affecting RAD51 expression in HR repair mechanisms.42, 43 miR‐103 and miR‐107 was shown to directly target and regulate RAD51D, which is critical for miR‐103/107–mediated chemosensitization.34 Hence, the mutations in miRNA target sites of RAD51D are also associated with the development of tumors. The gene discussed is RAD51; the disease is cancer.