ZHX2 and hepatocellular carcinoma: The increased expression of the examined four genes gain more importance in the context of their extensive gene network. Zhx2 (also known as RAF) has previously been associated with Hodgkin lymphoma [65] and hepatocellular carcinoma [66]; Abi1 (abl interactor 1) has a role in colorectal carcinoma development and invasion [67] and also in neuroblastoma propagation [68].