ADIPOQ and non-alcoholic fatty liver: In the earlier period, our group investigated the mechanism of QHD in some aspects of the pathological mechanism of nonalcoholic fatty liver (NAFL), indicating that the mechanism of QHD in preventing and treating NAFL involves regulation of adenosine monophosphate-activated protein kinase (AMPK) activity, elevation of adiponectin, regulation of intestinal flora, reduction of free fatty acid (FFA) toxicity, etc. [16–19].