Despite the significant effect of stroke on morbidity and mortality in the U.S., much of the literature for AIS focuses on the importance of minimizing treatment delays in patients who present to the ED within the tPA treatment window.13–19 As acknowledged in a statement from the AHA, the weak link in applying stroke treatments is patient delay in seeking care.20 Unfortunately, our results mirror those reported in the literature over the past 30 years, which show that the vast majority of patients are excluded from treatment due to delays in presentation.20–28. Here, PLAT is linked to stroke disorder.