Moreover, previous study has reported that TRPA1 and TRPM8 were expressed in human melanoma [15, 32]; our data showed that TRPA1 protein increased in all four melanoma cells (Figure 1(a)(v)), and TRPM8 protein level was increased in A375 and A2058 cells compared to melanocytes (Figure 1(a)(vi)). Here, TRPA1 is linked to melanoma.