In our study, the patients in the CKD group were those with moderate-to-advanced renal failure who did not receive dialysis, whereas in the study of Seeger et al., the serum vaspin levels were found to be as high as 2.4 ± 2.5 ng/ mL in the healthy control group and 12.6 ± 12.2 ng/ mL in the non-diabetic patients with CKD. This evidence concerns the gene SERPINA12 and chronic kidney disease.