ADIPOQ and obesity due to melanocortin 4 receptor deficiency: Adiponectin improving insulin capacity and creating anti-atherogenic and anti-inflammatory impacts,5 this hormone regulates blood glucose level.6 Plasma level of adiponectin reduces in obesity, diabetes, in patients with metabolic disorder and cardiovascular issues.5 Low plasma adiponectin concentration is an alarming situation for cardiovascular illnesses.7 According to various epidemiological studies Plasma adiponectin level is inversely related to adipose tissue mass.8