Common variants, G>A/A, (rs1227051, c.4723G>A) in CDH23 were identified in both brothers in homozygous form which had also been reported in Korean HL patients as a non-synonymous mutation.21 The same variation is presumed as polymorphism in Japanese population with NSHL.22 Therefore, the present study is an agreement with previous studies. Here, CDH23 is linked to Hodgkins lymphoma.