demonstrated that the BRD9 domain of SWI-SNF facilitates the leukemogenic ability of this chromatin-remodeling complex by facilitating the Myc transcription, the induction of cellular proliferation, and the inhibition of hematopoietic differentiation (Hohmann et al., 2016) that characterizes acute myeloid leukemia. Here, MYC is linked to acute myeloid leukemia.