ACLY and cancer: Cancer cells activate de novo lipogenesis by upregulation of key enzymes in lipid metabolism, some of which, such as AcetylCo-A Lyase (ACLY), AcetylCo-A Carboxylase (ACC) and Stearoyl-CoA desaturase-1 (SCD), are targets of pharmacological inhibitors to decrease cancer proliferation (Zaidi et al., 2012; Zu et al., 2013; Peck and Schulze, 2016; Stoiber et al., 2018).