Myc regulation of the cellular metabolic milieu is highly similar in Drosophila to the regulation found in tumor cells (DeBerardinis et al., 2008), indeed it was shown that in cells undergoing to a metabolic stress (starvation or competitive environment), expression of Myc switched their metabolism to increase glycolysis, glutaminolysis (Parisi et al., 2013; de la Cova et al., 2014; Hsieh et al., 2015), or lipid metabolism to favor survival by inducing autophagy (Parisi et al., 2013; Paiardi et al., 2017). Here, MYC is linked to neoplasm.