MAPK8 and cancer: Other studies highlighted the role of hemocytes in the interplay between inflammation and cancer, i.e., using a classic cancer model that recapitulates the hallmarks of epithelial cancer cells (Rasv12/scribble−/−), it was shown that cancer cells induce hemocyte's recruitment and proliferation in vivo by activating JNK signaling to cause the expression of JAK/STAT cytokines (Pastor-Pareja et al., 2008).