TGFB1 and breast carcinoma: The mammary neutrophil recruitment induced by this hormone was observed in other in vitro and in vivo breast cancer research, in which it promoted N2-neutrophil polarization, correlated with the overexpression of integrin LFA-1 and TGF-β, intra- and extravasation and trans-endothelial breast cancer cell migration, and with major breast tumor growth; this last effect was reversed by ICI 182,780 treatment.