miRNA target prediction with TargetScan showed that FAM83F mRNA 3′-UTR contains multiple binding sites for miRNAs highly expressed in normal thyroid, such as miR-143, miR-125b, miR-29a, miR-30a, miR-30c, miR-30d, and miR-22 (42), indicating that downregulation of these miRNAs in thyroid cancer would potentially increase FAM83F protein levels. Here, SACK1F is linked to thyroid gland carcinoma.