MAPT and Alzheimer disease: In a cohort of memory clinic patients and cognitively healthy elderly volunteers we found lower extraversion and openness to correlate with CSF markers of AD pathology: tau, ptau-181, tau/Aβ1–42, and ptau-181/Aβ1–42 ratios, but not with the Aβ1–42 level (Tautvydaite et al., 2017).