In this manuscript, we use the same method to deliver PTX to cancer cells: NLC is the PTX carrier with the surface modified with PEG and AR at the distal end of PEG (A-P-NLC) to achieve the active targeting effect towards the EGFR overexpressed NCI-H1299 cells (Han et al., 2013; Liao et al., 2015). This evidence concerns the gene EGFR and cancer.