We found that not only in iPS cells of αSyn A53T PD patient (Suppl Fig. 2d) but also in neurons derived from iPS cells of PD patient carrying αSyn A53T mutant (Fig. 1c), the protein level of ClpP was decreased when compared to that in isogenic corrected iPS cells and their derived neuronal culture, respectively (Suppl Figs. 2d, 1c). Here, CLPP is linked to Parkinson disease.