Although FABP5 has been shown to be pro-inflammatory in several models, including high fat diet-induced skin inflammation [15], allergic asthma [16], LPS-induced liver damage [17] and neuropathic pain in mice [18], in this study we show that in the lungs of mice exposed to CS and infection, FABP5 expression, or re-expression, decreases inflammation. Here, FABP5 is linked to Cowden syndrome 1.