MYB and acute myeloid leukemia: Moreover, inspection of known Myb target genes revealed a significant repression of Bcl2 (Taylor et al, 1996; Salomoni et al, 1997), a known anti-apoptotic regulator, in KL cells; concomitantly, we observed the up-regulation of a pro-apoptotic gene normally anti-correlated with Myb in AML, namely, Bcl2l11 (Bim) (Jing et al, 2015), in LL cells.