CEBPA and acute myeloid leukemia: The reduced dependency of Nter/Nter–mutant C/EBPα–driven AML cells on Myb is also paralleled by very little change in the number of genes affected by Myb knockdown, including no effect on Gfi1 or Sbno2. Interestingly, Myb targets the expression of the Cebpa gene itself in the wild-type and Cter/Nter C/EBPα contexts, suggesting positive feedback that is not seen in C/EBPα Nter/Nter cells.