Furthermore, we reported a strong linear correlation between expression of the two transcription factors and FLT3 RNA levels in human CN-AML, adding to an increasing body of evidence that points to MYB being a crucial component of leukaemia maintenance and oncogene addiction (Hess et al, 2006; Zuber et al, 2011; Clarke et al, 2017). This evidence concerns the gene MYB and acute myeloid leukemia.