This analysis was then reduced to a subset of 195 tumors consisting of: HGNET-MN1 (n = 21); PXA (n = 44); supratentorial ependymoma with C11orf95-RELA fusion (EPN-RELA; n = 70); supratentorial pilocytic astrocytoma and ganglioglioma (LGG-PA/GG-ST; n = 24); control reactive cortex (CONTR-REACT; n = 23); and control cerebral hemisphere (CONTR-HEMI; n = 13) (Fig. 1; Additional file 2: Figure S2). Here, RELA is linked to supratentorial ependymoma.