However, there were no changes in the protein expressions of PGC-1 α, markers of lipolysis (genes adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), comparative gene identification-58 (CGI-58), perilipin 1) and other markers related to adipose tissue inflammation (TNFα, IL-6, MCP-1, cluster of differentiation 68 (CD68)), browning (cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA), PRDM16), mitochondrial biogenesis (PGC-1α) and adipokine expression (autosomal dominant polycystic kidney disease (ADPK), leptin (LEP)). The gene discussed is PNPLA2; the disease is autosomal dominant polycystic kidney disease.