SNCA and neurodegenerative disease: Synucleinopathies refer to a group of neurodegenerative diseases, namely Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy, characterized histologically by the presence of inclusions (Lewy bodies and Lewy neurites) composed of aggregated α-synuclein in the central nervous system (CNS) [23,24].