SLC12A5 and epilepsy: Qualitatively our simulations do not contradict to their study, however quantitatively the potassium currents through voltage-gated and synaptic channels dominate over the KCC2-mediated potassium fluxes, and initial accumulation [K]o that triggers spontaneous discharges is evoked rather by the diffusion with the high-potassium bath solution, according to our experimental model of epilepsy.