Overall, each patient presented 1 to 7 risk factors for FN in addition to age (median number of 3): no prophylactic antibiotic treatment (84.5%), advanced stage (51.8%), female gender (47.9%), Hb level < 12 g/dL (41.5%), heart disease (19.7%), malnutrition (13.5%), renal failure (5.7%), history of febrile neutropenia (5.5%). The gene discussed is GSTM1; the disease is heart disorder.