IKZF1 and acute lymphoblastic leukemia: Despite of the strong association between PAX5 CNAs and IKZF1 deletions (Fig. 2, OR = 2.94, p < 0.001), CNAs in PAX5 were not predictive for high MRD levels (Fig. 3C) nor a poor prognosis in pediatric BCP-ALL cases (Fig. 4A).