GHR is a risk factor for some cancers, such as colorectal carcinoma, melanoma, uterine cervical neoplasms, breast cancer, and hepatocellular carcinoma.13 However, we found GHR was elevated in gastric cancer for the first time in this study, suggesting that GHR may be a risk factor for gastric cancer as well. Here, GHR is linked to colorectal carcinoma.