The antibody array utilized in this study simultaneously detected 40 cytokines and identified eleven cytokines (IFNGR1, Notch‐3, TNFRSF19L, GHR, SLAMF8, FR‐beta, Integrin alpha 5, Galectin‐8, EphA1, Epiregulin and FGF‐12) significantly elevated in gastric cancer serum when compared to the controls by Mann‐Whitney U test analysis. Here, NOTCH3 is linked to gastric cancer.