A study concerning AML identified 37 patients with mutation in one of the cohesin genes and, among them, the 81.1% had an additional mutation in genes causative for AML insurgence such as FLT3-ITD (21.6%), NPM1 (21.6%), RUNX1 or ASXL1 (Tsai et al., 2017). Here, NPM1 is linked to acute myeloid leukemia.