IL-10 production is related to genetic variations in its promoter region (Westendorp et al., 1997), and this region controls transcription and contains SNPs that are related to diabetes and its complication (Turner et al., 1997; Tegoshi et al., 2002; Mohebbatikaljahi et al., 2009; Mahmoud et al., 2016). Here, IL10 is linked to diabetes mellitus.