Elevated levels of anti-thyroid peroxidase antibodies (anti-TPOAb) and/or anti-thyroglobulin antibodies (anti-TgAb) are important laboratory characteristics for the diagnosis of Hashimoto's encephalopathy; elevated anti-thyroid peroxidase antibody levels are most common and are observed in 86% of patients with Hashimoto's encephalopathy, while 48% of the patients with Hashimoto's encephalopathy have elevated anti-thyroglobulin antibody levels (6). The gene discussed is TG; the disease is hereditary elliptocytosis.