Although very few studies have dissected the importance of ILC2 and ILC3 in apicomplexan infection, there are hints that these cells are responding to these infections and could either be protective, helping to dampen inflammation (NK-ILC1-IL-10, ILC2-IL-33, ILC3-IL22) or potentiating inflammatory pathology (NK-ILC1-IFNγ ILC3-IL-17). This evidence concerns the gene IFNG and infection.