After 8 weeks of moderate intensity exercise, there were concomitant rises in insulin sensitivity in PCOS patients (glucose disposal mg/kg/min: PCOS pre-exercise 3.25 ± 0.76; post-exercise 3.95 ± 1.45; p = 0.13), and in controls (glucose disposal mg/kg/min: controls pre-exercise 4.8 ± 1.64; post-exercise 5.79 ± 1.74; p < 0.02). This evidence concerns the gene INS and polycystic ovary syndrome.