Using IBM Watson 5 new RNA-Binding Proteins (RBPs) were identified which were previously not linked to ALS; Heterogeneous nuclear ribonucleoprotein U (hnRNPU), Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP), Putative RNA-binding protein 3 (RBMS3), ell Cycle Associated Protein 1 (Caprin-1) and Nucleoporin-like 2 (NUPL2). Here, CAPRIN1 is linked to amyotrophic lateral sclerosis.