C6orf141 and neoplasm: As presented in Table 3, low C6orf141 expression was significantly associated with advanced pathological stage (I vs II + II + IV, P = 0.001), large tumor size (T1 vs T1 + 2 + 3, P = 0.002), and advance N stage (N0 vs N1 + N2, P = 0.032) in patients with OSCC, whereas a higher C6orf141 expression level was weakly correlated with older patients (P = 0.062).