We also studied a mouse line which has a Pkd1 deletion and is therefore considered as a mouse ADPKD line, as expected curcumin blocked the growth of cysts at day 2 with 100 μM of curcumin, while day 6 and day 9 50 and 100μΜ were able to cause a block in the growth of cysts (Fig. 5C). This evidence concerns the gene PKD1 and autosomal dominant polycystic kidney disease.