Additionally, amongst patients receiving maintenance rituximab, KIR3DL1+/Bw4+ patients had improved outcome compared to those that were not KIR3DL1+/Bw4+ (p < 0.05 for TTRF, Fig. 2a; p = 0.01 for duration of response, Fig. 2b; and a trend of p = 0.07 for tumor shrinkage, Fig. 2c). The gene discussed is KIR3DL1; the disease is neoplasm.