TNNI3 and myocardial ischemia: On contrast, the diagnosis of post−/perioperative myocardial ischemia is grounded on elevated serum creatinine kinase (CK), CK-MB or cardiac troponin I (cTNI) levels, and the elevation of these serum markers within the first 24 h are associated with increased intermediate- and long-term mortality [1, 2].