In patients with IPF, rs35705950, the minor allele of a single nucleotide polymorphism (SNP) in MUC5B, a gene encoding a component of mucus secretions, has been associated with improved survival [94] while rs5743890, the minor allele of an SNP of TOLLIP (toll interacting protein), has been associated with worse survival [95]. The gene discussed is TOLLIP; the disease is idiopathic pulmonary fibrosis.