MALAT1 promotes EMT of nasopharyngeal carcinoma cells through de-repressing Capn4 by sponging miR-124 [48] and mediates TGF-β1-induced EndMT by regulating TGFBR2 and SMAD3 through miR-145 in endothelial progenitor cells (EPCs) [25]. The gene discussed is SMAD3; the disease is nasopharyngeal carcinoma.