Nevertheless, it was shown that TrkB signaling in Müller cells, but not in retinal ganglion and amacrine cells, is deeply involved in neural protection and regeneration during retinal degeneration [26] and that the BDNF-induced protection of photoreceptors from light damage is mediated by activation of truncated TrkB expressed by Müller cells [27]. The gene discussed is NTRK2; the disease is retinal degeneration.