Smithuis et al gave single high dose PQ, 0.75 mg/kg, to 397 malaria infected patients of all ages who were treated with four ACTs in Myanmar where the moderately severe Mahidol variant has a prevalence of ~10% [6]; PQ was well tolerated but G6PD status not determined and Hb measured only on D0 and D63 [25]. Here, GSTM1 is linked to malaria.