TBX5 and posterior cortical atrophy: Interestingly, network analysis revealed interactions among germline and somatically mutated genes containing germline mutations with strong associations to PCa, including, KLK3, C9orf3, GLI2, KLK15, JAZF1, IRX4, NKX3–1, FGF10, RASAI, TBX5 and TERT (Fig. 4).