The most significant pathways included the MSP-RON, Prostate cancer, P53, PDGF, MYC mediated apoptosis, molecular mechanisms of cancer, GP6, TR/RxR activation, EGF, ERBB2-ERBB3, PTEN and prolactin signaling pathways (Fig. 7). The gene discussed is PTEN; the disease is Familial prostate cancer.