A germline SNV and a tumor SNV were identified in ADCY8 and HSPG2 genes, whereas a germline SNV/indel and somatic LOH of the wild-type allele was predicted for BRCA2, BLM, ERCC2, PARP2, RECQL, REV3L, RIF1, SEC23B, SMARCA4 and STK11IP. This evidence concerns the gene HSPG2 and neoplasm.