Interestingly, multivariate survival analysis elucidated a significantly poorer prognosis in lung and gastric cancer when GLS/GLS2 expression was low/high compared to co-occurrence (high/high) or non-co-occurrence (low/low) (Figure 7b(iii,iv)), suggesting that a partial-co-occurrence of GLS/GLS2 may regulate cancer prognosis. The gene discussed is GLS2; the disease is cancer.