CCL2 and neoplasm: The key characteristics of cancer-related inflammation include infiltration of white blood cells; prominence of tumor-associated macrophages; the presence of polypeptide messengers of inflammatory cytokines, such as tumor necrosis factor (TNF), interleukin (IL)-1, and IL-6; chemokines, such as CCL2; and the occurrence of tissue remodeling and angiogenesis [7].