TGFB1 and colitis: In the same way, in a mice model of famoxadone-induced colitis, orally GMP induced body weight restoration and intestinal injury reduction, in association with a decrease in CD4, CD8, mucosal addressin cell adhesion molecule-1 (MAdCAM), mitogen extracellular-signal-regulated kinase kinase-1 (MEKK1), and Smad7 (a molecule that transduces TGF-β signaling) intestinal expression [75].