Conversely, in a Chinese cohort of leprosy patients, genetic variants of FCN2 (-557A>G and +6424G>T) in the promoter region and exon 8, respectively, were linked to low L-ficolin levels and had a positive association with leprosy susceptibility [106], which is in opposition to both H- and M-ficolin, where higher concentrations of either of these results in enhanced susceptibility [95, 107]. This evidence concerns the gene FCN2 and leprosy.