In order to comprehensively and accurately evaluate the genomic alterations in bladder cancer, a gene set containing four identified genes (EGF, EGFR, THBS1, and VEGFA) performed as in the study of The Cancer Genome Atlas Research Network 17, whose genomic profiles included additional mRNA and protein expression levels compared to the other six studies. The gene discussed is EGFR; the disease is urinary bladder carcinoma.