Based on the direct targets found by DrugBank and associated genes generated by STRING, we further performed pathway enrichment analysis through WebGestalt; the bladder cancer pathway and phosphoinositide 3‐kinase (PI3K)–AKT pathway were screened, and then seven overlapping genes were identified to further analyze their genomic alterations through the cBioPortal database. This evidence concerns the gene PIK3CA and urinary bladder cancer.