TSPY1 and hepatocellular carcinoma: Indeed, as described above, the survival data indicate that, while there was no significant difference between female HCC group and the male TSPY-silent HCC group, the survival ratio of the male TSPY-high HCC group was significantly lower than that of female HCC group (Log-rank test P-value = 0.0164) with 3 years survival ratio of 35% in the male TSPY-high HCC group and 60–70% in female HCC and the male TSPY-silent HCC groups respectively (Fig. 3b).