To identify the common DEGs associated with both TSPY overexpression in HuH-7 cells and TSPY high expression in HCC patients, we had analyzed the differential gene expression patterns of HuH-7 cells overexpressing TSPY versus EGFP and those of TSPY-high group versus TSPY-silent group in clinical HCC tissue samples. Here, TSPY1 is linked to hepatocellular carcinoma.