Based on the microarray data analysis between PD and healthy controls by Limma, we obtained 394 DEGs, including 207 upregulated DEGs (such as insulin-like growth factor-1 receptor (IGF1R) and RPS4Y1) and 187 downregulated DEGs (such as DLG1 and PURG), and 7 DElncRNAs, including 2 upregulated DElncRNAs (LINC00302 and LINC00328) and 5 downregulated DElncRNAs (FAM215A, MCF2L-AS1, NOP14-AS1, PART1, and XIST). The gene discussed is RPS4Y1; the disease is Parkinson disease.