SOD1 and sexually transmitted disease: After hypoxia/hypoperfusion in the brain, the content of MDA in white matter significantly increased, while the content of SOD in white matter decreased in VD rats (MDA, 18.53±1.55; SOD, 99.74±12.53; P < 0.05) compared with the sham group (MDA, 5.73±0.66; SOD, 249.86±22.51).